GLPMGR

Changing GLP-1 medicine

Changing GLP-1 medicine: what the product information says

Moving to a different GLP-1 medicine, between an injection and a tablet, or to a lower dose, a pause or a stop is a decision for you and your prescriber. Here is what the medicines’ own information says, word for word, and how GLPMGR keeps a record of it. It isn’t medical advice.

1. There’s no agreed dose conversion

There’s no agreed way to convert a dose from one GLP-1 medicine to another, even between brands of the same one, so your prescriber will tell you which dose to start on. The NHS Specialist Pharmacy Service says “There is very little data on how to switch between GLP-1 RAs, including brands containing the same type of GLP-1 RA”, and points prescribers to each medicine’s own starting doses (NHS SPS, updated November 2025).

2. Using two GLP-1 medicines together

Some medicines’ information says not to use them with another GLP-1 medicine. Where it does, this is its wording:

  • Wegovy injection and pill (US): “Concomitant use of WEGOVY (semaglutide) tablets or WEGOVY (semaglutide) injection with other semaglutide-containing products or with any other GLP-1 receptor agonist is not recommended.” Source
  • Zepbound (US): “Coadministration with other tirzepatide-containing products or with any glucagon-like peptide-1 (GLP-1) receptor agonist is not recommended.” Source
  • Wegovy (UK): “Do not use wegovy® in combination with other medicines that contain GLP-1 receptor agonists (such as liraglutide, dulaglutide, exenatide or lixisenatide).” Source (MHRA product search)
  • Saxenda (UK): “Do not use Saxenda in combination with other medicines that contain GLP-1 receptor agonists (such as exenatide or lixisenatide).” Source
  • Saxenda (US): “Coadministration with other liraglutide-containing products or with any other glucagon-like peptide-1 (GLP-1) receptor agonist is not recommended.” Source
  • Victoza (US): “Coadministration with other liraglutide-containing products is not recommended.” Source

We didn’t find this in the current information for Mounjaro, Ozempic or Trulicity, so nothing is quoted for them. Ask your prescriber or pharmacist about your own medicines.

3. Wegovy injection and the Wegovy pill (US)

The US prescribing information covers switching between the two:

  • “Patients taking WEGOVY 2.4 mg injection for cardiovascular risk reduction or weight reduction in adults may switch to WEGOVY 25 mg tablets.”
  • “One week after discontinuing WEGOVY 2.4 mg injection, initiate 25 mg of WEGOVY tablets orally once daily.”
  • “The day after discontinuing WEGOVY tablets 25 mg once daily, initiate WEGOVY 2.4 mg subcutaneous injection once weekly.”

From the Wegovy prescribing information and Medication Guide (injection and tablets), DailyMed, effective 06/2026.

4. Lowering, pausing or stopping

Any change to your dose, or stopping, is best agreed with your prescriber. If a change happens, keeping a record of it, and of how your weight and appetite go afterwards, gives you and your prescriber something to look at together.

5. In GLPMGR

  • A change of medicine is checked: when a new dose is a different medicine from the last one, GLPMGR says what changed, quotes the lines above where the product information has them, and offers to pause the old medicine’s reminders.
  • Log Treatment Change (Journey’s + menu) records a dose lowered or raised, a pause, a stop, a restart or a change of timing. Saving never changes your schedule; afterwards it offers to open your schedule so you can update it yourself.
  • Your record: changes appear in your timeline, as dashed lines on your weight charts and beside appetite by week in Weight Trends, in the doctor report, and in your backups.

Questions people ask

Can GLPMGR tell me what dose to start on after switching?

No. There's no agreed way to convert a dose from one GLP-1 medicine to another, so your prescriber tells you which dose to start on. GLPMGR follows the schedule you enter and never suggests a dose.

Can I log that my dose was lowered, paused or stopped?

Yes. Log Treatment Change, in Journey's + menu, records a dose lowered or raised, a pause, a stop, a restart or a change of timing, and who decided it if you want to say. It never changes your schedule by itself: afterwards it offers to open your schedule so you can update it.

Where do my treatment changes show up?

In your timeline, as dashed lines on your weight charts and the appetite chart in Weight Trends, in the doctor report, and in your backups and exports.

Does GLPMGR say whether a change was a good idea?

No. GLPMGR records what you tell it, in neutral words. Any change to your medicine is best agreed with your prescriber.

Try GLPMGR

A calm, private GLP-1 tracker for iPhone, iPad and Apple Watch. See injection sites by medicine, GLP-1 tablets and questions and answers. Download on the App Store